A halin yanzu, fiye da ƙasashe 100 neotame ya amince da amfani da su a cikin nau'ikan samfuran sama da 1000.
Ya dace a yi amfani da shi a cikin abubuwan sha masu laushi na carbonated, yogurts, kek, foda, kumfa mai kumfa a tsakanin sauran abinci.Ana iya amfani da shi azaman tebur saman zaki don abubuwan sha masu zafi kamar kofi.Yana rufe dandano mai ɗaci .
HuaSweet neotame ya dace da ma'aunin GB29944 na kasar Sin kuma yana cika ƙayyadaddun FCCVIII, USP, JECFA da EP.HuaSweet ta kafa cibiyar sadarwar tallace-tallace a cikin kasashe sama da tamanin a duk kudu maso gabashin Asiya, Turai, Amurka ta Kudu, Arewacin Amurka da Afirka.
A cikin 2002, FDA ta amince da shi azaman mai zaƙi mara gina jiki da haɓaka ɗanɗano a cikin Amurka a cikin abinci gabaɗaya, ban da nama da kaji.[3]A cikin 2010, an yarda da shi don amfani da abinci a cikin EU tare da lambar E961.[5]Hakanan an amince da ita azaman ƙari a cikin wasu ƙasashe da yawa a wajen Amurka da EU.
A cikin Amurka da EU, abin karɓa na yau da kullun (ADI) na neotame ga ɗan adam shine 0.3 da 2 mg a kowace kilogiram na nauyin jiki (mg/kg bw), bi da bi.NOAEL ga mutane shine 200 mg/kg bw kowace rana tsakanin EU.
Kiyasin yuwuwar abubuwan ci na yau da kullun daga abinci sun yi ƙasa da matakan ADI.Neotame da aka ci zai iya haifar da phenylalanine, amma a cikin amfani da neotame na yau da kullum, wannan ba shi da mahimmanci ga masu ciwon phenylketonuria.Hakanan ba shi da wani tasiri a cikin masu ciwon sukari na 2.Ba a la'akari da shi azaman carcinogenic ko mutagenic.
Cibiyar Kimiyya a cikin Sha'awar Jama'a tana matsayi neotame a matsayin mai aminci.